日 時：平成29年1月26日（木） 13:00-14:00
場 所：筑波大学 医学系エリア 睡眠医科学研究棟 1F 講堂
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利用停留所（関東鉄道バス）：筑波大学中央行き又は筑波大学循環バス「追越学生宿舎前」
演 者：Dr. Masabumi Minami （南 雅文先生）
Department of Pharmacology, Graduate School of Pharmaceutical Sciences,
Hokkaido University（北海道大学薬学研究院）
演 題:“How does pain induce negative emotion? Role of the bed nucleus of the stria terminalis in pain-induced aversion”
要 旨: Pain consists of sensory-discriminative and negative-affective components. Although the neuronal mechanisms underlying the sensory component of pain have been studied extensively, those underlying its affective component are only beginning to be elucidated. In this seminar, I will talk about 1) opposing roles of corticotropin-releasing factor (CRF) and neuropeptide Y (NPY) within the dorsolateral part of the bed nucleus of the stria terminalis (dlBNST) in pain-induced aversive behaviors, 2) opposing effects of CRF and NPY on neuronal excitability within dlBNST neurons, and 3) histological data suggesting the regulation of neuronal excitability of dopaminergic neurons in the ventral tegmental area (VTA) by VTA-projecting BNST output neurons.
Possible neuronal circuits for pain-induced aversion will be discussed.
問い合わせ：国際統合睡眠医科学研究機構 029-853-8080(内線8080)