日 時：平成28年11月14日（月） 12:00 – 13:00
場 所：筑波大学 睡眠医科学研究棟 1F 講堂
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利用停留所（関東鉄道バス）：筑波大学中央行き又は筑波大学循環バス「追越学生宿舎前」
演 者：Dr. Dr. Arisa Hirano
Department of Neurology, University of California, San Francisco
演 題:“Turnover of clock proteins determines the timing of sleep-wake behavior “
要 旨: Sleep is vital for all animals. The timing of sleep-wake cycle is regulated by an internal oscillator “circadian clock”, in which CRYPTOCHROME (CRY) proteins play an important role. CRY proteins gradually accumulate during day, and then CRY levels decline at night.
The protein turnover of CRY (balance between stabilization and degradation) is fine-tuned at the post-translational level throughout the day in order to generate the proper protein rhythms. In this seminar, I will talk about current understanding of regulatory mechanism of CRY proteins and our recent finding of a human mutation in CRY2 gene responsible for Familial Advanced Sleep Phase (FASP) trait.
問い合わせ：国際統合睡眠医科学研究機構
Tel : 029-853-8080